Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 3/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640435 | 0.83 | CYP3A4 (0.33) | CYP3A4TSHRALDH1A1TDP1HPGD | |
| SCHEMBL25418829 | 0.83 | CYP3A4 (0.33) | CYP3A4TSHRALDH1A1TDP1HPGD | |
| Hydrochloric Acid SCHEMBL27864578 | 0.81 | CYP3A4 (0.32) | CYP3A4TSHRALDH1A1TDP1HPGD | |
| SCHEMBL6431300 | 0.74 | DBH (0.37) | CYP3A4TSHRALDH1A1TDP1HPGD | |
| SCHEMBL8018526 | 0.74 | TSHR (0.38) | CYP3A4TSHRALDH1A1TDP1PARP1 | |
| SCHEMBL317892 | 0.70 | MAPT (0.40) | ALDH1A1TDP1PTPRCALOX15SMN1; SMN2 | |
| SCHEMBL8194088 | 0.68 | SMN1; SMN2 (0.46) | CYP3A4TSHRALDH1A1TDP1HPGD | |
| SCHEMBL21359837 | 0.68 | MAPT (0.38) | ALDH1A1TDP1PTPRCALOX15SMN1; SMN2 | |
| Water SCHEMBL27460917 | 0.68 | MAPT (0.38) | ALDH1A1TDP1PTPRCALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2948518 | 0.68 | MAPT (0.38) | ALDH1A1TDP1PTPRCALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | claimed |
| CN-116648622-A | Method for diagnosing and monitoring sepsis | 瑟罗克索有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-115536594-A | 5-amino-2,3-dihydrothiazine-1,4-dione crystal | 麦翠奥制药公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-109071461-B | Method for preparing 5-amino-2, 3-dihydrophthalazine-1, 4-diketone crystal | 麦翠奥制药公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-0799224-B1 | QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AG (DE) | 2002-04-17 | — | — | EP | disclosed |
| CN-1081636-C | Pyrrolyl quinoxalindiones, their production and use | BASF AG (DE) | 2002-03-27 | — | — | CN | disclosed |
| EP-0742217-B1 | Isoindoline pigments based on aminoquinoxalindiones | CLARIANT GMBH (DE) | 1999-06-23 | — | — | EP | disclosed |
| CN-1211980-A | Pyrrolyl quinoxalindiones, their production and use | BASF AG (DE) | 1999-03-24 | — | — | CN | disclosed |
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5849743-A | Quinoxalines and drugs prepared therefrom | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| CN-1152918-A | Novel amido quinoxaline diones, their preparation and use | BASF AG (DE) | 1997-06-25 | — | — | CN | disclosed |
| CN-1152918-A | Novel amido quinoxaline diones, their preparation and use | BASF AG (DE) | 1997-06-25 | — | — | CN | disclosed |
| EP-0742217-A1 | Isoindoline pigments based on aminoquinoxalindiones | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1996019476-A1 | NOVEL QUINOXALINES AND DRUGS PREPARED THEREFROM | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-27 | — | — | WO | disclosed |
| WO-1995035289-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0000737-B1 | MONOAZO PIGMENTS OF THE ACETOACETYLAMINO BENZIMIDAZOLONE SERIES, THEIR PREPARATION AND THEIR USE FOR COLOURING ORGANIC MATERIAL OF HIGH MOLECULAR WEIGHT | CIBA-GEIGY AG (CH) | 1981-04-29 | — | — | EP | disclosed |
| EP-0000737-A1 | Monoazo pigments of the acetoacetylamino benzimidazolone series, their preparation and their use for colouring organic material of high molecular weight | CIBA-GEIGY AG (CH) | 1979-02-21 | — | — | EP | disclosed |