SCHEMBL317892

SCHEMBL317892

O=C1N=c2ccccc2=NC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
LMNA P02545 3/20 0.40
MAOA P21397 3/20 0.40
POLB P06746 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
S100A4 P26447 2/20 0.40
KDM4E B2RXH2 2/20 0.40
PTPRC P08575 2/20 0.40
CES2 O00748 1/20 0.40
APAF1 O14727 1/20 0.40
TERT O14746 1/20 0.40
NPC1 O15118 1/20 0.40
PLIN1 O60240 1/20 0.40
TDP2 O95551 1/20 0.40
S1PR4 O95977 1/20 0.40
PLA2G1B P04054 1/20 0.40
BCHE P06276 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2948518 0.97 MAPT (0.38) MAPTKMT2AMEN1LMNAMAOA
SCHEMBL21359837 0.97 MAPT (0.38) MAPTKMT2AMEN1LMNAMAOA
Bicarbonate SCHEMBL9542773 0.89 NPSR1 (0.39) MAPTKMT2AMEN1LMNAPOLB
Phosphonic Acid SCHEMBL2459322 0.87 MAPT (0.35) MAPTKMT2AMEN1LMNAMAOA
SCHEMBL9093165 0.83 LMNA (0.37) MAPTKMT2AMEN1LMNAMAOA
SCHEMBL37950 0.80 MEN1 (0.35) MAPTKMT2AMEN1LMNAMAOA
Benzylamine SCHEMBL7955985 0.79 LOXL2 (0.58) MAOASMN1; SMN2MAOBCYP1A2
Water SCHEMBL11357123 0.78 APAF1 (0.33) MAPTKMT2AMEN1LMNAMAOA
SCHEMBL31241401 0.78 APAF1 (0.33) MAPTKMT2AMEN1LMNAMAOA
SCHEMBL640436 0.78 APAF1 (0.33) MAPTKMT2AMEN1LMNAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047727-A Method for preparing quinoxaline-2, 3-diketone compound by virtue of regioselective photocatalytic oxidation 浙江工业大学台州研究院 2024-05-17 CN claimed
CN-116789610-A Photocatalytic preparation method of quinoxaline-2, 3-diketone compound 湖南科技学院 2023-09-22 CN claimed
US-20210395445-A1 Heat and Aging Resistant Polyglycolide Copolymer and Composition Thereof PUJING CHEMICAL INDUSTRY CO., LTD. (CN) 2021-12-23 US claimed
EP-3873970-A1 HEAT AND AGING RESISTANT POLYGLYCOLIDE COPOLYMER AND COMPOSITION THEREOF Pujing Chemical Industry Co., Ltd (CN) 2021-09-08 EP claimed
CN-112469763-A High temperature and aging resistant polyglycolide copolymers and compositions thereof 上海浦景化工技术股份有限公司 2021-03-09 CN claimed
CN-107337964-B Colored liquid metal printing ink and preparation method thereof 北京梦之墨科技有限公司 2020-07-07 CN claimed
WO-2019177117-A1 DRUG FOR TREATING COUGH 日本ケミファ株式会社 2019-09-19 WO claimed
US-20170072005-A1 COMBINATIONS OF NMDAR MODULATING COMPOUNDS UNIV NORTHWESTERN (US) 2017-03-16 US claimed
EP-3139943-A1 COMBINATIONS OF NMDAR MODULATING COMPOUNDS Northwestern University (US) 2017-03-15 EP claimed
EP-2983473-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF ALS Mountain Llc (US) 2016-02-17 EP claimed
WO-1993008188-A1 TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1993-04-29 WO claimed
EP-0518909-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. HOECHST AG (DE) 1992-12-23 EP claimed
EP-0316649-B1 WATER INSOLUBLE AZO COLOURING AGENTS, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-22 EP claimed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO claimed
US-5039528-A EAA antagonists as anti-emetic drugs OLNEY JOHN W (US) 1991-08-13 US claimed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US claimed
EP-0432994-A2 Excitatory amino acid antagonists as anti-emetic drugs Olney, John William (US) 1991-06-19 EP claimed
EP-0424179-A2 Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration Olney, John William (US) 1991-04-24 EP claimed
EP-0224086-B1 SUBSTITUTED BENZYL ETHERS BAYER AG (DE) 1990-10-24 EP claimed
EP-0316649-A2 Water insoluble azo colouring agents, their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170072005-A1 COMBINATIONS OF NMDAR MODULATING COMPOUNDS GRIN1, GRIN2A, GRIN3A MAPT 1043/4885KMT2A 1130/4885MEN1 4095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.