Sugi Predict

Sugi Predict / Compounds / Dimethylamine

Dimethylamine

Dimethylamine

SCHEMBL7487471

CNC.O=C1C=C(c2ccccc2)c2ccccc2C1=O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 12/20 0.85
▸ PTPRC P08575 8/20 0.85
▸ PTPRF P10586 2/20 0.85
▸ CDC25B P30305 2/20 0.85
▸ BACE1 P56817 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29808966 0.92 PTPN1 (1.00) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL6236312 0.92 PTPN1 (1.00) PTPN1PTPRCPTPRFCDC25BBACE1
Diethylamine SCHEMBL7475236 0.86 PTPN1 (0.74) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL5139479 0.80 PTPN1 (0.76) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL30433091 0.80 PTPN1 (0.76) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL8600693 0.80 PTPN1 (0.75) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL6236908 0.79 PTPRC (1.00) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL7487467 0.77 PTPN1 (0.67) PTPN1PTPRCPTPRFCDC25B
SCHEMBL29673492 0.76 BACE1 (1.00) PTPN1PTPRCPTPRFCDC25BBACE1
SCHEMBL5485068 0.76 BACE1 (1.00) PTPN1PTPRCPTPRFCDC25BBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1025107-B1 PHOTOCHROMIC COMPOUNDS JAMES ROBINSON LTD (GB) 2002-08-07 — — EP disclosed
US-6303673-B1 FOR OPTICAL ELEMENTS JAMES ROBINSON LIMITED (GB) 2001-10-16 — — US disclosed