SCHEMBL7487490

SCHEMBL7487490

O=CCCCCCCN1C(=O)C2CC2C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
RECQL P46063 2/20 0.42
ESR1 P03372 1/20 0.42
POLB P06746 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
EPHX2 P34913 5/20 0.36
TSHR P16473 2/20 0.34
MGLL Q99685 3/20 0.34
HTT P42858 2/20 0.34
USP2 O75604 1/20 0.34
HSD17B10 Q99714 1/20 0.34
FAAH O00519 2/20 0.33
HSP90AA1 P07900 1/20 0.33
TLR9 Q9NR96 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7483124 0.84 MEN1 (0.43) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL7483484 0.84 MEN1 (0.43) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL25095762 0.78 MEN1 (0.78) MEN1KMT2ARAB9AALDH1A1TDP1
SCHEMBL7479037 0.77 MEN1 (0.47) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL7490240 0.77 PTGS1 (0.52) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL7481753 0.77 PTGS1 (0.52) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL7480871 0.77 HTT (0.51) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL7483292 0.77 HTT (0.51) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL7482405 0.77 PTGS1 (0.52) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL14191452 0.75 MEN1 (0.48) MEN1KMT2ARAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929522-B1 INSECT-REPELLENT FORMULATIONS PFIZER LTD (GB) 2002-12-18 EP disclosed
US-6130241-A Insect-repellent formulations PFIZER INC. (US) 2000-10-10 US disclosed
EP-0929522-A1 INSECT-REPELLENT FORMULATIONS Pfizer Limited (GB) 1999-07-21 EP disclosed
WO-1998013345-A1 INSECT-REPELLENT FORMULATIONS PFIZER LIMITED (GB) 1998-04-02 WO disclosed