Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7483292 | 1.00 | HTT (0.51) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL2768849 | 0.92 | HTT (0.59) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL16039625 | 0.83 | USP2 (0.44) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL7481753 | 0.80 | PTGS1 (0.52) | ALDH1A1KMT2AMEN1RAB9ARECQL | |
| SCHEMBL7490240 | 0.80 | PTGS1 (0.52) | ALDH1A1KMT2AMEN1RAB9ARECQL | |
| SCHEMBL7482405 | 0.80 | PTGS1 (0.52) | ALDH1A1KMT2AMEN1RAB9ARECQL | |
| SCHEMBL7479037 | 0.80 | MEN1 (0.47) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL22895251 | 0.78 | USP2 (0.54) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL14191452 | 0.78 | MEN1 (0.48) | HTTHSD17B10USP2TSHRALDH1A1 | |
| SCHEMBL7485374 | 0.78 | ALDH1A1 (0.46) | HTTHSD17B10USP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929522-B1 | INSECT-REPELLENT FORMULATIONS | PFIZER LTD (GB) | 2002-12-18 | — | — | EP | disclosed |
| US-6130241-A | Insect-repellent formulations | PFIZER INC. (US) | 2000-10-10 | — | — | US | disclosed |