Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 12/20 | 0.53 |
| ▸ | PPARA | Q07869 | 12/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029491 | 0.90 | FFAR1 (0.54) | FFAR1KDRKDM4EPPARGPPARA | |
| SCHEMBL4030301 | 0.84 | KDR (0.61) | FFAR1KDRKDM4EPPARGPPARA | |
| SCHEMBL4038160 | 0.81 | KDR (0.53) | FFAR1KDRKDM4EPPARGPPARA | |
| SCHEMBL4035439 | 0.81 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL4031813 | 0.79 | KDR (0.64) | FFAR1KDRKDM4EPPARGPPARA | |
| SCHEMBL6998371 | 0.79 | KDM4E (0.53) | FFAR1KDRKDM4EPPARGPPARA | |
| SCHEMBL2672791 | 0.78 | GABRA5 (0.64) | — | |
| SCHEMBL4845837 | 0.78 | FFAR1 (0.50) | FFAR1KDRKDM4EPPARGPPARA | |
| SCHEMBL4029981 | 0.77 | KDR (0.61) | FFAR1KDRPPARGPPARAMAPT | |
| SCHEMBL4037802 | 0.77 | KDM4E (0.50) | FFAR1KDRKDM4EPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |