Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834163 | 0.86 | TSHR (0.33) | — | |
| SCHEMBL238978 | 0.78 | — | — | |
| SCHEMBL1358657 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL9596829 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL7668804 | 0.70 | GABRP (0.31) | — | |
| SCHEMBL623051 | 0.67 | MAPK1 (0.35) | — | |
| SCHEMBL520941 | 0.67 | — | — | |
| SCHEMBL20803956 | 0.63 | — | — | |
| SCHEMBL3875145 | 0.62 | — | — | |
| SCHEMBL10414450 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091741-A4 | AZEPINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | LILLY CO ELI (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1091741-A1 | AZEPINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000203-A1 | AZEPINE DERIVATIVES HAVING EFFECTS ON SEROTONIN RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |