Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750907 | 0.93 | MAPT (0.35) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL749615 | 0.93 | MAPT (0.35) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL747204 | 0.92 | MAPT (0.35) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL748640 | 0.91 | TACR3 (0.32) | MAPTTP53SMN1; SMN2LMNADHODH | |
| SCHEMBL750906 | 0.90 | TP53 (0.39) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL749783 | 0.90 | TACR3 (0.32) | MAPTTP53SMN1; SMN2LMNADHODH | |
| SCHEMBL747958 | 0.86 | TP53 (0.38) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL748502 | 0.85 | DHODH (0.33) | MAPTSMN1; SMN2MEN1KMT2APPARG | |
| SCHEMBL747946 | 0.85 | TP53 (0.40) | MAPTTP53SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL748627 | 0.84 | DHODH (0.33) | MAPTSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |