Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750906 | 0.96 | TP53 (0.39) | TP53MAPTSRCLMNASLC13A5 | |
| SCHEMBL749665 | 0.93 | MAPT (0.42) | TP53MAPTSRCLMNASLC13A5 | |
| SCHEMBL745530 | 0.90 | HDAC1 (0.41) | SRCSLC13A5MEN1KMT2ALPAR1 | |
| SCHEMBL747722 | 0.89 | ESRRG (0.41) | TP53MAPTSRCLMNASLC13A5 | |
| SCHEMBL751065 | 0.88 | SRC (0.38) | TP53MAPTSRCLMNASLC13A5 | |
| SCHEMBL749993 | 0.88 | LPAR1 (0.39) | MAPTSRCLMNASLC13A5SMN1; SMN2 | |
| SCHEMBL748116 | 0.88 | SRC (0.39) | SRCLMNASLC13A5LPAR1LPAR5 | |
| SCHEMBL748197 | 0.87 | SRC (0.36) | TP53MAPTSRCLMNASLC13A5 | |
| SCHEMBL748241 | 0.87 | LPAR1 (0.36) | TP53MAPTSRCSLC13A5KMT2A | |
| SCHEMBL748805 | 0.86 | MAPT (0.36) | TP53MAPTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |