Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304113 | 0.81 | ADORA1 (0.68) | ADORA1IGF1RMAPK1PTGDR2PDE4B | |
| SCHEMBL3616432 | 0.78 | ADORA1 (0.59) | ADORA1IGF1RMAPK1PTGDR2PDE4B | |
| SCHEMBL8810012 | 0.78 | ADORA1 (0.73) | ADORA1IGF1RMAPK1KDM4EHSD17B10 | |
| SCHEMBL7291999 | 0.78 | ADORA1 (0.63) | ADORA1IGF1RMAPK1PTGDR2PDE4B | |
| SCHEMBL8639797 | 0.77 | ADORA1 (0.72) | ADORA1IGF1RMAPK1PTGDR2KDM4E | |
| SCHEMBL19829271 | 0.77 | ADORA1 (0.66) | ADORA1IGF1RMAPK1PDE4BPDE3A | |
| SCHEMBL7295203 | 0.76 | ADORA1 (0.73) | ADORA1IGF1RMAPK1PDE4BPDE3A | |
| SCHEMBL7299166 | 0.76 | ADORA1 (0.77) | ADORA1IGF1RMAPK1KDM4EMAPK3 | |
| SCHEMBL7301059 | 0.76 | ADORA1 (0.67) | ADORA1IGF1RMAPK1PTGDR2PDE4B | |
| Hydrochloric Acid SCHEMBL7301696 | 0.75 | ADORA1 (0.68) | ADORA1IGF1RMAPK1KDM4EMAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925299-B1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6124456-A | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0925299-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998003507-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |