Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458309 | 0.79 | PDE7A (0.35) | EPAS1SQORPDE7AGAATSHR | |
| SCHEMBL6589014 | 0.75 | ALDH1A1 (0.41) | PDE7AGAACYP3A4LMNAALDH1A1 | |
| SCHEMBL6589021 | 0.73 | KDM4E (0.42) | LMNAALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL31165729 | 0.70 | GRM4 (0.41) | GAACYP3A4TSHRLMNANFKB1 | |
| SCHEMBL855507 | 0.70 | GRM4 (0.41) | GAACYP3A4TSHRLMNANFKB1 | |
| SCHEMBL6011402 | 0.70 | CASP1 (0.42) | TLR8MGAMGAASIMGAM2 | |
| SCHEMBL6984484 | 0.69 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2KDM4EMAPTHSD17B10 | |
| SCHEMBL6772176 | 0.68 | EPAS1 (0.32) | EPAS1 | |
| SCHEMBL6573783 | 0.68 | PDE10A (0.50) | TLR8MGAMGAASIMGAM2 | |
| SCHEMBL6772566 | 0.65 | ALDH1A1 (0.33) | GAASCN9AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177193-A1 | PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000049016-A1 | PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-08-24 | — | — | WO | disclosed |