Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 10/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490417 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2HPGDEGLN2 | |
| SCHEMBL4816609 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2HPGDEGLN2 | |
| SCHEMBL8916786 | 0.89 | TSHR (0.40) | ALDH1A1KDM4ESMN1; SMN2HPGDEGLN2 | |
| SCHEMBL4821987 | 0.89 | TSHR (0.40) | ALDH1A1KDM4ESMN1; SMN2HPGDEGLN2 | |
| SCHEMBL7492040 | 0.89 | HTR1A (0.35) | ALDH1A1SMN1; SMN2EGLN2TSHRPOLB | |
| SCHEMBL4811365 | 0.88 | ALDH1A1 (0.35) | ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL4820334 | 0.86 | TSHR (0.43) | ALDH1A1KDM4ESMN1; SMN2EGLN2TSHR | |
| SCHEMBL7492281 | 0.86 | EGLN2 (0.38) | ALDH1A1KDM4ESMN1; SMN2HPGDEGLN2 | |
| SCHEMBL7490029 | 0.86 | GLA (0.40) | KDM4EEGLN2TSHRLMNAGLA | |
| SCHEMBL4820465 | 0.86 | PDE2A (0.39) | ALDH1A1SMN1; SMN2HPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945453-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | BASF AG (DE) | 2002-11-20 | — | — | EP | claimed |
| EP-0945453-A1 | Fungicidal trifluorophenyl-triazolopyrimidines | American Cyanamid Company (US) | 1999-09-29 | — | — | EP | claimed |
| EP-0945453-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | BASF AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-6117865-A | FOR CONTROLLING FUNGUS IN PLANTS | AMERICAN CYANAMID COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0945453-A1 | Fungicidal trifluorophenyl-triazolopyrimidines | American Cyanamid Company (US) | 1999-09-29 | — | — | EP | disclosed |