Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481800 | 0.94 | GPR119 (0.49) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7481263 | 0.85 | ALDH1A1 (0.45) | GPR119NSD2 | |
| SCHEMBL7481717 | 0.85 | GPR119 (0.48) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7481127 | 0.84 | GPR119 (0.47) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7479402 | 0.83 | GPR119 (0.46) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7478740 | 0.83 | GPR119 (0.46) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7483410 | 0.82 | GPR119 (0.45) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7484237 | 0.82 | SLC22A12 (0.50) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7478361 | 0.81 | GPR119 (0.44) | GPR119NSD2ALKCHEK2TBK1 | |
| SCHEMBL7483548 | 0.81 | SLC22A12 (0.49) | GPR119NSD2ALKCHEK2TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865281-B1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 2002-04-03 | — | — | EP | disclosed |
| US-5849759-A | Naphthyl-substituted benzimidazole derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-15 | — | — | US | disclosed |