Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475252 | 0.86 | KDM4E (0.38) | NR1H2GABRG2GABRB3GABRA5TLR9 | |
| SCHEMBL7483264 | 0.86 | KDM4E (0.38) | NR1H2GABRG2GABRB3GABRA5CA12 | |
| SCHEMBL7478776 | 0.84 | PIK3R1 (0.32) | NR1H2GABRG2GABRB3GABRA5TLR9 | |
| SCHEMBL7487767 | 0.84 | TLR9 (0.34) | NR1H2GABRG2GABRB3GABRA5TLR9 | |
| SCHEMBL7480954 | 0.83 | ESR2 (0.41) | NR1H2GABRG2GABRB3GABRA5NR1H3 | |
| SCHEMBL862090 | 0.81 | PIK3R1 (0.37) | NR1H2GABRG2GABRB3GABRA5NR1H3 | |
| SCHEMBL30847402 | 0.79 | USP30 (0.39) | NR1H2NR1H3ALDH1A1KMT2A | |
| SCHEMBL3756850 | 0.79 | CCNB2 (0.41) | NR1H2GABRG2GABRB3GABRA5NR1H3 | |
| SCHEMBL12158 | 0.79 | USP30 (0.39) | NR1H2NR1H3ALDH1A1KMT2A | |
| SCHEMBL7484622 | 0.79 | BRD4 (0.34) | NR1H2GABRG2GABRB3GABRA5NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865281-B1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 2002-04-03 | — | — | EP | disclosed |
| US-5849759-A | Naphthyl-substituted benzimidazole derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-15 | — | — | US | disclosed |