Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7479742 | 0.81 | LIPE (0.51) | LIPEL3MBTL1AKR1C3NAMPTGRIN2D | |
| SCHEMBL7477425 | 0.79 | ACHE (0.46) | LIPERAB9ABCHE | |
| SCHEMBL7549708 | 0.77 | LIPE (1.00) | LIPENPC1RAB9APRMT5WDR77 | |
| SCHEMBL7484036 | 0.77 | ACHE (0.43) | LIPERAB9ABCHE | |
| SCHEMBL7477903 | 0.76 | EED (0.54) | LIPENAMPTGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7550918 | 0.75 | LIPE (0.81) | LIPENPC1RAB9APRMT5WDR77 | |
| SCHEMBL7550712 | 0.75 | LIPE (0.80) | LIPENPC1RAB9APRMT5WDR77 | |
| SCHEMBL7549145 | 0.75 | LIPE (1.00) | LIPEL3MBTL1NPC1RAB9A | |
| SCHEMBL7555453 | 0.75 | LIPE (0.80) | LIPENPC1RAB9APRMT5WDR77 | |
| SCHEMBL7557024 | 0.75 | LIPE (1.00) | LIPEL3MBTL1AKR1C3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |