Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451480 | 1.00 | SLC6A4 (0.52) | SLC6A4HRH3SPHK2CASRSPHK1 | |
| SCHEMBL7490906 | 0.83 | SLC6A4 (0.52) | SLC6A4HRH3 | |
| SCHEMBL7447108 | 0.83 | MEN1 (0.39) | SLC6A4HRH3 | |
| SCHEMBL7496052 | 0.83 | MEN1 (0.39) | SLC6A4HRH3 | |
| SCHEMBL7495148 | 0.81 | SPHK1 (0.40) | SLC6A4SPHK2SPHK1 | |
| SCHEMBL7491381 | 0.81 | HRH3 (0.40) | SLC6A4HRH3 | |
| SCHEMBL7440202 | 0.80 | HRH3 (0.47) | SLC6A4HRH3SPHK2CASR | |
| SCHEMBL7440197 | 0.80 | HRH3 (0.47) | SLC6A4HRH3SPHK2CASR | |
| SCHEMBL7491392 | 0.79 | SLC6A4 (0.42) | SLC6A4HRH3 | |
| SCHEMBL7490466 | 0.79 | HRH3 (0.37) | SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |