Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440197 | 1.00 | HRH3 (0.47) | HRH3SLC6A4CASRSPHK2SIGMAR1 | |
| SCHEMBL7491577 | 0.86 | NOS2 (0.43) | HRH3SLC6A4KCNH2 | |
| SCHEMBL7485123 | 0.85 | FAAH (0.50) | SLC6A4SIGMAR1 | |
| SCHEMBL7485116 | 0.85 | FAAH (0.50) | SLC6A4SIGMAR1 | |
| SCHEMBL7494040 | 0.82 | F10 (0.44) | HRH3SIGMAR1 | |
| SCHEMBL7490175 | 0.80 | SLC6A4 (0.52) | HRH3SLC6A4CASRSPHK2 | |
| SCHEMBL7451480 | 0.80 | SLC6A4 (0.52) | HRH3SLC6A4CASRSPHK2 | |
| SCHEMBL7449835 | 0.79 | CCR4 (0.43) | SIGMAR1 | |
| SCHEMBL7487800 | 0.79 | CCR4 (0.43) | SIGMAR1 | |
| SCHEMBL7488521 | 0.77 | SLC6A4 (0.37) | HRH3SLC6A4CASRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |