Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490470 | 1.00 | TPSAB1 (0.38) | TPSAB1EPHX1SIRT2SIRT1SIRT3 | |
| SCHEMBL7490519 | 0.83 | IDO1 (0.49) | TPSAB1MAPT | |
| SCHEMBL7490523 | 0.83 | IDO1 (0.49) | TPSAB1MAPT | |
| SCHEMBL15298425 | 0.79 | TPSAB1 (0.51) | TPSAB1EPHX1SIRT2SIRT1SIRT3 | |
| SCHEMBL7493856 | 0.76 | GAA (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL7493852 | 0.76 | GAA (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL15298501 | 0.72 | TPSAB1 (0.45) | TPSAB1EPHX1SIRT2SIRT1SIRT3 | |
| SCHEMBL7491115 | 0.71 | GAA (0.33) | GAA | |
| SCHEMBL7492787 | 0.71 | KDM4E (0.34) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL7491118 | 0.71 | GAA (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5677322-A | THERAPY FOR AGING, DIABETES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |