Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SORD | Q00796 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282298 | 0.89 | KDM4E (0.43) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1713664 | 0.81 | KDM4E (0.49) | KDM4ESORDLMNAL3MBTL1SLC6A7 | |
| SCHEMBL2320496 | 0.79 | SORD (0.51) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL18228513 | 0.79 | SORD (0.51) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31014265 | 0.79 | SORD (0.51) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL28282315 | 0.79 | KDM4E (0.41) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL468382 | 0.78 | SORD (0.50) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL30785422 | 0.78 | SORD (0.50) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2320514 | 0.78 | SORD (0.50) | KDM4ESORDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1266496 | 0.76 | SORD (0.49) | KDM4ESORDLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563016-A | Using single hydrogen perfluoro alkane as the manufacturing method of the all-fluoroalkyl compound of starting material | 关东电化工业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| EP-1146871-A4 | ANTIDEPRESSANT HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2002-04-17 | — | — | EP | disclosed |
| CN-1342074-A | Antidepressant heterocyclic compounds | BRISTOL MYERS SQUIBB CO (US) | 2002-03-27 | — | — | CN | disclosed |
| EP-1146871-A1 | ANTIDEPRESSANT HETEROCYCLIC COMPOUNDS | Bristol-Myers Squibb Company (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6225324-B1 | POTENT INHIBITION OF 5-HT REUPTAKE; 1,3-DISUBSTITUTED PYRROLIDINE, 1,4-DISUBSTITUTED PIPERIDINE, OR 1,4-DISUBSTITUTED HEXAHYDROAZEPINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY | 2001-05-01 | — | — | US | disclosed |
| WO-2000044376-A1 | ANTIDEPRESSANT HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| US-4751305-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| US-4748246-A | INTERLEUKIN ANTAGONISTS, ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
| US-4302455-A | ANALGESICS, ANTIDEPRESSANTS | MERCK & CO., INC. (US) | 1981-11-24 | — | — | US | disclosed |