Sugi Predict

Sugi Predict / Compounds / SCHEMBL468382

SCHEMBL468382

SCHEMBL468382

c1cnc(N2CCCCC2)cn1

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SORD Q00796 1/20 0.50
▸ KDM4E B2RXH2 5/20 0.49
▸ LMNA P02545 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ SLC6A7 Q99884 1/20 0.44
▸ GPR119 Q8TDV5 2/20 0.43
▸ HTR1A P08908 1/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.42
▸ HRH4 Q9H3N8 1/20 0.42
▸ CNR2 P34972 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ DRD4 P21917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2320514 1.00 SORD (0.50) SORDKDM4ELMNAL3MBTL1SLC6A7
SCHEMBL30785422 1.00 SORD (0.50) SORDKDM4ELMNAL3MBTL1SLC6A7
SCHEMBL2320496 0.98 SORD (0.51) SORDKDM4ELMNAL3MBTL1SLC6A7
SCHEMBL18228513 0.98 SORD (0.51) SORDKDM4ELMNAL3MBTL1SLC6A7
SCHEMBL31014265 0.98 SORD (0.51) SORDKDM4ELMNAL3MBTL1SLC6A7
Thiophene SCHEMBL26658665 0.88 L3MBTL1 (0.44) SORDKDM4ELMNAL3MBTL1SLC6A7
SCHEMBL25378983 0.81 CHRNB2 (0.55) KDM4EHTR1AHRH4ALDH1A1
SCHEMBL19035674 0.81 HRH4 (0.50) SORDKDM4ELMNAL3MBTL1HTR1A
SCHEMBL30306065 0.81 CHRNB2 (0.55) KDM4EHTR1AHRH4ALDH1A1
Piperidine SCHEMBL1270139 0.81 PLD1 (0.50) SORDKDM4ELMNAL3MBTL1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102260218-B Synthesis method of aminopyrazine spice BEIJING INST TECHNOLOGY 2013-05-08 — — CN claimed
CN-102260218-A Synthesis method of aminopyrazine spice — 2011-11-30 — — CN claimed
WO-2009018368-A1 COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) 2009-02-05 — — WO claimed
EP-1466906-A1 Heterocyclic urea and related compounds useful as anti-inflammatory agents BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2004-10-13 — — EP claimed
JP-2002539198-A — — 2002-11-19 — — JP claimed
US-6358945-B1 CYTOKINE, TUMOR NECROSIS FACTOR, AND INTERLEUKIN INHIBITORS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2002-03-19 — — US claimed
EP-1165516-A2 HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2002-01-02 — — EP claimed
WO-2000055139-A2 HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2000-09-21 — — WO claimed
US-20260001859-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. 2026-01-01 — — US disclosed
WO-2025226510-A1 LPAR1 INHIBITORS ABBVIE INC. (US) 2025-10-30 — — WO disclosed
US-20250289798-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. 2025-09-18 — — US disclosed
US-12319668-B2 Small molecule inhibitors of mammalian SLC6A19 function JNANA THERAPEUTICS INC. (US) 2025-06-03 — — US disclosed
US-20250115570-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. 2025-04-10 — — US disclosed
US-20240208923-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION JNANA THERAPEUTICS INC. 2024-06-27 — — US disclosed
WO-2000055139-A2 HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2000-09-21 — — WO disclosed
CN-1035112-C Improved process for useful diazinylpiperides derivatives BRISTOR MYERS SQUIBB CO (US) 1997-06-11 — — CN disclosed
CN-1012364-B PREPARATION FOR DINITROGEN HETEROBENZOPIPERIDINE DERIVATIVES OF CYCLIC AMIDE AND IMIDE FOR CURING ELDER MENTAL PATIENT BRISTOL MYERS CO (US) 1991-04-17 — — CN disclosed
US-4826843-A Cerebral function enhancing diazinylpiperidine derivatives BRISTOL-MYERS (US) 1989-05-02 — — US disclosed
US-4826843-A Cerebral function enhancing diazinylpiperidine derivatives BRISTOL-MYERS (US) 1989-05-02 — — US disclosed
US-4826843-A Cerebral function enhancing diazinylpiperidine derivatives BRISTOL-MYERS (US) 1989-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208923-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION SLC18A2, SLC6A19, SLC1A1 SORD 687/4885KDM4E 4275/4885LMNA 3886/4885
US-12319668-B2 Small molecule inhibitors of mammalian SLC6A19 function SLC18A2, SLC6A19, SLC1A1 SORD 687/4885KDM4E 4275/4885LMNA 3886/4885
US-20250115570-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION SLC18A2, SLC6A19, SLC1A1 SORD 687/4885KDM4E 4275/4885LMNA 3886/4885
US-20250289798-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION SLC18A2, SLC6A19, SLC1A1 SORD 687/4885KDM4E 4275/4885LMNA 3886/4885
US-20260001859-A1 SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION SLC6A19, SLC6A15, SLC6A2 SORD 1084/4885KDM4E 1420/4885LMNA 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.