Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487750 | 0.95 | MAPK1 (0.37) | EGLN2MAPK1ALDH1A1TSHRPOLB | |
| SCHEMBL7490009 | 0.94 | KMT2A (0.38) | EGLN2MAPK1ALDH1A1TSHRKMT2A | |
| SCHEMBL7496989 | 0.94 | KMT2A (0.38) | EGLN2MAPK1ALDH1A1TSHRKMT2A | |
| SCHEMBL6867351 | 0.86 | LMNA (0.38) | EGLN2ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL7495679 | 0.83 | GABBR2 (0.39) | KDM4E | |
| SCHEMBL7958606 | 0.83 | EGLN2 (0.39) | EGLN2MAPK1ALDH1A1TSHRKDM4E | |
| SCHEMBL4817675 | 0.82 | LMNA (0.39) | MAPK1ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL4816384 | 0.81 | CDK2 (0.35) | EGLN2MAPK1ALDH1A1TSHRPOLB | |
| SCHEMBL978477 | 0.81 | KMT2A (0.36) | EGLN2MAPK1ALDH1A1TSHRKMT2A | |
| SCHEMBL6187065 | 0.80 | SMN1; SMN2 (0.38) | EGLN2MAPK1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945453-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | BASF AG (DE) | 2002-11-20 | — | — | EP | claimed |
| EP-0945453-A1 | Fungicidal trifluorophenyl-triazolopyrimidines | American Cyanamid Company (US) | 1999-09-29 | — | — | EP | claimed |
| EP-0945453-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | BASF AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-6117865-A | FOR CONTROLLING FUNGUS IN PLANTS | AMERICAN CYANAMID COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0945453-A1 | Fungicidal trifluorophenyl-triazolopyrimidines | American Cyanamid Company (US) | 1999-09-29 | — | — | EP | disclosed |