SCHEMBL7493407

SCHEMBL7493407

O=C(C1=CSC=CN1C(=O)CC1Cc2ccccc2C1)C1CCN[C@@H]1C(O)=S

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PREP P48147 14/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7324059 0.83 IDH1 (0.33)
SCHEMBL7327641 0.78 PREP (0.42) PREP
SCHEMBL7328709 0.78 PREP (0.35) PREP
SCHEMBL8160490 0.75 PREP (0.35) PREP
SCHEMBL7490666 0.74 PREP (0.33) PREP
SCHEMBL7324397 0.74 PREP (0.47) PREP
SCHEMBL7350647 0.73 PREP (0.39) PREP
SCHEMBL7318772 0.72 GAA (0.32) PREP
SCHEMBL7354544 0.72 PREP (0.51) PREP
SCHEMBL8153384 0.71 PREP (0.56) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed