SCHEMBL7490706

SCHEMBL7490706

CCc1n[c]n2nccc2n1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7488427 0.86 KDM4E (0.31) ADORA2AADORA1
SCHEMBL7493607 0.75
SCHEMBL7491168 0.69 NPC1 (0.43) ADORA2AADORA1
SCHEMBL7486187 0.67
SCHEMBL7490786 0.66 PRKAB2 (0.37) ADORA2AADORA1
SCHEMBL23913613 0.59 DYRK1A (0.33)
SCHEMBL17690933 0.58 PRKAB2 (0.49)
SCHEMBL5753997 0.58
SCHEMBL2270761 0.57 DDAH1 (0.32) ADORA2AADORA1
SCHEMBL6468289 0.57 DYRK1A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0915093-B1 AMIDE DERIVATIVES OTSUKA PHARMA CO LTD (JP) 2002-11-27 EP disclosed
US-6166016-A Amide derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-12-26 US disclosed
EP-0915093-A1 AMIDE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1999-05-12 EP disclosed