Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 7/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779815 | 0.81 | SKP2 (0.47) | IGF1RALOX15SKP2 | |
| SCHEMBL11038670 | 0.79 | IGF1R (0.33) | IGF1RALOX15SKP2 | |
| SCHEMBL11193422 | 0.78 | SLC6A4 (0.31) | — | |
| SCHEMBL5537061 | 0.75 | SLC6A4 (0.44) | — | |
| SCHEMBL7628388 | 0.75 | MAPT (0.52) | IGF1RALOX15 | |
| SCHEMBL5181629 | 0.75 | MIF (0.31) | IGF1RALOX15 | |
| SCHEMBL5181634 | 0.75 | SLC6A2 (0.31) | IGF1RALOX15 | |
| SCHEMBL7628384 | 0.75 | BACE1 (0.32) | IGF1RALOX15 | |
| SCHEMBL3021345 | 0.73 | SLC6A4 (0.42) | — | |
| SCHEMBL11043970 | 0.72 | BACE1 (0.41) | IGF1RALOX15SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5677322-A | THERAPY FOR AGING, DIABETES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0638075-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| WO-1994019335-A1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |