SCHEMBL7628384

SCHEMBL7628384

CSc1ccc(CC[O])cc1SC

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.32
LCK P06239 1/20 0.32
IAPP P10997 2/20 0.31
KCNJ1 P48048 1/20 0.30
KCNH2 Q12809 1/20 0.30
IGF1R P08069 1/20 0.30
ALOX15 P16050 1/20 0.30
GRIA2 P42262 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
PTGS1 P23219 1/20 0.30
BLM P54132 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2090990 0.83 HPGD (0.31) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL5181629 0.79 MIF (0.31) IGF1RALOX15
SCHEMBL5181634 0.79 SLC6A2 (0.31) IGF1RALOX15GRIA2
SCHEMBL7628388 0.79 MAPT (0.52) BACE1IGF1RALOX15KDM4EALDH1A1
SCHEMBL8779815 0.78 SKP2 (0.47) LCKIAPPIGF1RALOX15KDM4E
SCHEMBL7490805 0.75 IGF1R (0.39) IGF1RALOX15
SCHEMBL7786392 0.74 TTR (0.33) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL11193422 0.74 SLC6A4 (0.31) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL5181553 0.74 IDO1 (0.41) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL5181545 0.74 SLC6A4 (0.31) KDM4EALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458908-B1 A PROCESS FOR PREPARING A SULFUR-CONTAINING UNSATURATED CARBOXYLATE COMPOUND AS CLAIMED IN CLAIM 1 COMPRISING REACTING A SULFUR-CONTAINING DERIVATIVE FOR OPTICAL POLYMERS MITSUI CHEMICALS, INC. (JP) 2002-10-01 US disclosed
EP-1057808-A2 Sulfur-containing unsaturated carboxylate compound and its use Mitsui Chemicals, Inc. (JP) 2000-12-06 EP disclosed