Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490820 | 1.00 | DPP4 (0.45) | DPP4DPP8DPP9SLC6A4RORC | |
| SCHEMBL7490293 | 0.90 | DPP4 (0.44) | DPP4DPP8DPP9SLC6A4KDM4E | |
| SCHEMBL7490288 | 0.90 | DPP4 (0.44) | DPP4DPP8DPP9SLC6A4KDM4E | |
| SCHEMBL7488534 | 0.86 | RORC (0.42) | DPP4DPP8DPP9SLC6A4RORC | |
| SCHEMBL7488548 | 0.86 | RORC (0.42) | DPP4DPP8DPP9SLC6A4RORC | |
| SCHEMBL7536225 | 0.85 | RORC (0.39) | SLC6A4RORCKDM4EALDH1A1TSHR | |
| SCHEMBL7536239 | 0.85 | RORC (0.39) | SLC6A4RORCKDM4EALDH1A1TSHR | |
| SCHEMBL7485095 | 0.84 | SLC6A4 (0.39) | DPP4SLC6A4RORC | |
| SCHEMBL7485089 | 0.84 | SLC6A4 (0.39) | DPP4SLC6A4RORC | |
| SCHEMBL7493336 | 0.81 | RORC (0.39) | SLC6A4RORCKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |