Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488534 | 1.00 | RORC (0.42) | RORCSLC6A4HRH3MTNR1AMTNR1B | |
| SCHEMBL7493324 | 0.93 | RORC (0.39) | RORCSLC6A4HRH3MTNR1AMTNR1B | |
| SCHEMBL7493336 | 0.93 | RORC (0.39) | RORCSLC6A4HRH3MTNR1AMTNR1B | |
| SCHEMBL27535674 | 0.91 | MTNR1A (0.38) | RORCSLC6A4HRH3MTNR1AMTNR1B | |
| SCHEMBL7536225 | 0.88 | RORC (0.39) | RORCSLC6A4HRH3HCRTR1HCRTR2 | |
| SCHEMBL7536239 | 0.88 | RORC (0.39) | RORCSLC6A4HRH3HCRTR1HCRTR2 | |
| SCHEMBL7485095 | 0.86 | SLC6A4 (0.39) | RORCSLC6A4HRH3CHRM3DPP4 | |
| SCHEMBL7490826 | 0.86 | DPP4 (0.45) | RORCSLC6A4KDM4EALDH1A1TSHR | |
| SCHEMBL7490820 | 0.86 | DPP4 (0.45) | RORCSLC6A4KDM4EALDH1A1TSHR | |
| SCHEMBL7485089 | 0.86 | SLC6A4 (0.39) | RORCSLC6A4HRH3CHRM3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079396-C | Aromatic amidine derivatives useful as selective thrombin inhibitors | C & C RES LAB (KR) | 2002-02-20 | — | — | CN | disclosed |
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| CN-1219932-A | Aromatic amidine derivatives useful as selective thrombin inhibitors | C & C RESEARCH LAB (KR) | 1999-06-16 | — | — | CN | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |