Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.54 |
| ▸ | ITGAV | P06756 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490874 | 0.89 | ITGB3 (0.66) | ITGB3ITGAVITGA2BSCN3A | |
| SCHEMBL7486656 | 0.88 | ITGB3 (0.58) | ITGB3ITGAVITGA2B | |
| SCHEMBL7486439 | 0.84 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL7493829 | 0.83 | ITGB3 (0.61) | ITGB3ITGAVITGA2B | |
| SCHEMBL8459092 | 0.79 | ITGAV (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL7486179 | 0.79 | ITGB3 (0.54) | ITGB3ITGAVITGA2B | |
| SCHEMBL8802938 | 0.79 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7403276 | 0.79 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL7402138 | 0.78 | ITGB3 (0.55) | ITGB3ITGAVITGA2B | |
| SCHEMBL8903718 | 0.77 | ITGB3 (0.53) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760658-B1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-0760658-A4 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0760658-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO. INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032710-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO., INC. (US) | 1995-12-07 | — | — | WO | disclosed |