Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 17/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 15/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3756583 | 0.77 | CYP11B2 (0.47) | CYP11B2CYP11B1SLC22A12 | |
| SCHEMBL751926 | 0.73 | CYP11B2 (0.43) | CYP11B2CYP11B1 | |
| SCHEMBL748530 | 0.70 | CYP11B2 (0.68) | CYP11B2CYP11B1 | |
| SCHEMBL3742204 | 0.70 | CYP11B2 (0.48) | CYP11B2CYP11B1SLC22A12 | |
| SCHEMBL746742 | 0.70 | CYP11B2 (0.49) | CYP11B2CYP11B1SLC22A12 | |
| SCHEMBL3747120 | 0.69 | CYP11B2 (0.46) | CYP11B2CYP11B1 | |
| SCHEMBL3477444 | 0.68 | CYP11B2 (0.53) | CYP11B2CYP11B1SLC22A12 | |
| SCHEMBL744419 | 0.68 | SLC22A12 (0.35) | SLC22A12 | |
| SCHEMBL746962 | 0.67 | CYP11B2 (0.58) | CYP11B2CYP11B1 | |
| SCHEMBL746772 | 0.67 | CYP11B2 (0.54) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429995-A1 | ARYL PYRIDINE AS ALDOSTERONE SYNTHASE INHIBITORS | Novartis AG (CH) | 2012-03-21 | — | — | EP | disclosed |