Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 9/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494365 | 1.00 | KYNU (0.59) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL24130581 | 0.86 | KYNU (0.62) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL3249670 | 0.86 | KYNU (0.62) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL24130582 | 0.86 | KYNU (0.62) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL6498057 | 0.86 | KYNU (0.62) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL13369139 | 0.85 | KYNU (0.60) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL13625105 | 0.85 | KYNU (0.60) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL29095981 | 0.85 | KYNU (0.63) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL18328213 | 0.85 | KYNU (0.63) | KYNUALDH1A1ALOX15CTSKTRPM8 | |
| SCHEMBL8438035 | 0.84 | ALDH1A1 (0.60) | KYNUALDH1A1ALOX15CTSKTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208097-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | Aventis Pharmaceuticals Inc. (US) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001007436-A2 | SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-02-01 | — | — | WO | disclosed |