Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501373 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP2D6CYP2C19L3MBTL1SMN1; SMN2 | |
| SCHEMBL7494427 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL7494425 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL7491268 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL9408173 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL1754710 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL2115865 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT | |
| SCHEMBL7501371 | 0.75 | CYP2D6 (0.36) | TSHRCYP2D6CYP2C19MAPTMMP1 | |
| SCHEMBL7501368 | 0.75 | CYP2D6 (0.36) | TSHRCYP2D6CYP2C19MAPTMMP1 | |
| SCHEMBL1261327 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TSHRL3MBTL1CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |