Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822429 | 0.86 | ADRA2A (0.39) | NQO2TNFRIPK1AHRBRD4 | |
| SCHEMBL3630725 | 0.73 | NQO2 (0.41) | NQO2TXNRD1TXNRD3TXNRD2ALDH1A1 | |
| SCHEMBL14070148 | 0.72 | MAPT (0.40) | NQO2TXNRD1TXNRD3TXNRD2ALDH1A1 | |
| SCHEMBL29591462 | 0.69 | TNF (0.54) | TNFRIPK1AHRBRD4TAF1 | |
| SCHEMBL1374474 | 0.69 | TNF (0.54) | TNFRIPK1AHRBRD4TAF1 | |
| SCHEMBL4829239 | 0.69 | TNF (0.35) | TNFRIPK1AHRBRD4TAF1 | |
| SCHEMBL29532058 | 0.69 | TNF (0.35) | TNFRIPK1AHRBRD4TAF1 | |
| SCHEMBL9740011 | 0.68 | NQO2 (0.40) | NQO2TXNRD1TXNRD3TXNRD2ALDH1A1 | |
| SCHEMBL5760178 | 0.68 | QPCT (0.42) | NQO2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL4824761 | 0.67 | HTR2C (0.40) | TNFRIPK1AHRBRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586171-A | Indole derivative, pharmaceutical composition and application thereof in central nervous field | 长春金赛药业有限责任公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-113754631-B | Heteroaryl method of indole | 中国科学院理化技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| EP-1165511-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058286-A2 | METHOD OF PRODUCING HETEROCYCLIC CARBAMATES FROM AZA-HETEROCYCLIC COMPOUNDS AND CARBON DIOXIDE | Gödecke GmbH (DE) | 2000-10-05 | — | — | WO | disclosed |