Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498547 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| SCHEMBL30673688 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| SCHEMBL1644002 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| SCHEMBL2342479 | 0.83 | ALDH1A1 (0.55) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11760825 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| SCHEMBL1279094 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| SCHEMBL4463532 | 0.81 | CA1 (0.70) | ALDH1A1HPGDCA1CA2CA9 | |
| SCHEMBL31309573 | 0.81 | CA1 (0.70) | ALDH1A1HPGDCA1CA2CA9 | |
| SCHEMBL29350373 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 | |
| SCHEMBL7219508 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDSLC40A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5677322-A | THERAPY FOR AGING, DIABETES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |