Sugi Predict

Sugi Predict / Compounds / SCHEMBL2342479

SCHEMBL2342479

SCHEMBL2342479

CC(=O)Nc1ccccc1S(=O)(=O)O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.55
▸ HPGD P15428 1/20 0.55
▸ CASP6 P55212 1/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ SLC40A1 Q9NP59 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ PKM P14618 1/20 0.50
▸ TSHR P16473 3/20 0.49
▸ LMNA P02545 1/20 0.49
▸ POLB P06746 2/20 0.49
▸ CA1 P00915 2/20 0.49
▸ CA2 P00918 2/20 0.49
▸ MAOA P21397 1/20 0.49
▸ CA9 Q16790 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ MAPK1 P28482 1/20 0.47
▸ NAPRT Q6XQN6 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30673688 1.00 ALDH1A1 (0.55) ALDH1A1HPGDCASP6SMN1; SMN2SLC40A1
Hydrochloric Acid SCHEMBL11760825 0.98 ALDH1A1 (0.53) ALDH1A1HPGDCASP6SMN1; SMN2SLC40A1
SCHEMBL1644002 0.85 ALDH1A1 (0.55) ALDH1A1HPGDSMN1; SMN2SLC40A1HTT
SCHEMBL498547 0.85 ALDH1A1 (0.55) ALDH1A1HPGDSMN1; SMN2SLC40A1HTT
SCHEMBL10893116 0.84 CA2 (0.54) ALDH1A1SMN1; SMN2HTTLMNACA1
SCHEMBL29350373 0.83 ALDH1A1 (0.53) ALDH1A1HPGDSMN1; SMN2SLC40A1HTT
SCHEMBL7494652 0.83 ALDH1A1 (0.53) ALDH1A1HPGDSMN1; SMN2SLC40A1HTT
SCHEMBL31309573 0.83 CA1 (0.70) ALDH1A1HPGDCA1CA2CA9
SCHEMBL1279094 0.83 ALDH1A1 (0.53) ALDH1A1HPGDSMN1; SMN2SLC40A1HTT
SCHEMBL4463532 0.83 CA1 (0.70) ALDH1A1HPGDCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107474070-A A kind of preparation method of environment-protecting and non-poisonous phosphorous melamine expanding fire retardant oligomer 绵阳旺通科技有限公司 2017-12-15 — — CN claimed
EP-0555400-B1 POLYACRYLIC ACID COMPOSITIONS FOR TEXTILE PROCESSING PEACH STATE LABS INC (US) 2003-04-09 — — EP claimed
US-5602277-A Substituted benzene derivatives useful as neuraminidase inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 1997-02-11 — — US claimed
US-5384252-A Cyclization of an unsaturated molecule with sulfonate leaving group THE SCRIPPS RESEARCH INSTITUTE (US) 1995-01-24 — — US claimed
EP-0555400-A4 POLYACRYLIC ACID COMPOSITIONS FOR TEXTILE PROCESSING — 1993-10-06 — — EP claimed
EP-0555400-A1 POLYACRYLIC ACID COMPOSITIONS FOR TEXTILE PROCESSING PEACH STATE LABS, INC. (US) 1993-08-18 — — EP claimed
WO-1992007883-A1 POLYACRYLIC ACID COMPOSITIONS FOR TEXTILE PROCESSING PEACH STATE LABS, INC. (US) 1992-05-14 — — WO claimed
WO-2021114460-A1 METHOD FOR PRODUCING P-ACETAMIDOBENZENESULFONYL CHLORIDE BY MEANS OF DOUBLE-TEMPERATURE-ZONE TWO-STAGE METHOD BASED ON CONTINUOUS FLOW REACTION 山东金德新材料有限公司 2021-06-17 — — WO disclosed
US-20180153817-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA, INC. (US) 2018-06-07 — — US disclosed
CN-107556221-A The preparation method of para-ester 新乡市锦源化工有限公司 2018-01-09 — — CN disclosed
CN-107474070-A A kind of preparation method of environment-protecting and non-poisonous phosphorous melamine expanding fire retardant oligomer 绵阳旺通科技有限公司 2017-12-15 — — CN disclosed
EP-2710431-B1 TONER CANON KK (JP) 2017-09-13 — — EP disclosed
US-20170157059-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS ALA WAI PHARMA, INC. (US) 2017-06-08 — — US disclosed
WO-1992007883-A1 POLYACRYLIC ACID COMPOSITIONS FOR TEXTILE PROCESSING PEACH STATE LABS, INC. (US) 1992-05-14 — — WO disclosed
US-4612394-A Process for producing aminophenyl-β-hydroxyethylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-09-16 — — US disclosed
EP-0095177-B1 PROCESS FOR THE PREPARATION OF N-ACETYLAMINO-ARYL-SULPHONIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-24 — — EP disclosed
US-4487725-A Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-11 — — US disclosed
EP-0120807-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-10-03 — — EP disclosed
EP-0095177-A1 Process for the preparation of N-acetylamino-aryl-sulphonic acids HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-30 — — EP disclosed
EP-0092909-A2 Process for producing aminophenyl-beta-hydroxyethylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170157059-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SLC35A1, SLC29A2, NEU2 ALDH1A1 3807/4885HPGD 1015/4885CASP6 3739/4885
US-20180153817-A1 FORMULATIONS FOR ENHANCED BIOAVAILABILITY OF ORALLY ADMINISTERED POLAR AGENTS SLC35A1, SLC29A2, NEU2 ALDH1A1 3807/4885HPGD 1015/4885CASP6 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.