Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18758397 | 0.90 | NLRP3 (0.40) | NLRP3L3MBTL1GAAKDM4ELMNA | |
| SCHEMBL6161648 | 0.88 | MAPK1 (0.42) | NLRP3L3MBTL1GAAKDM4ELMNA | |
| SCHEMBL16964041 | 0.87 | KMT2A (0.47) | L3MBTL1KDM4ELMNAALDH1A1TSHR | |
| SCHEMBL1867904 | 0.84 | NLRP3 (0.54) | NLRP3L3MBTL1GAAKDM4ELMNA | |
| SCHEMBL3888694 | 0.83 | KDM4E (0.45) | NLRP3L3MBTL1GAAKDM4ELMNA | |
| SCHEMBL7880397 | 0.83 | KDM4E (0.48) | NLRP3L3MBTL1KDM4ELMNAALDH1A1 | |
| SCHEMBL22655985 | 0.81 | SMN1; SMN2 (0.44) | L3MBTL1GAALMNAALDH1A1HSD17B10 | |
| SCHEMBL1477877 | 0.81 | PKM (0.44) | NLRP3L3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL38652331 | 0.81 | PKM (0.44) | NLRP3L3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL12023029 | 0.79 | NLRP3 (0.50) | NLRP3L3MBTL1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945453-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | BASF AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-6117865-A | FOR CONTROLLING FUNGUS IN PLANTS | AMERICAN CYANAMID COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0945453-A1 | Fungicidal trifluorophenyl-triazolopyrimidines | American Cyanamid Company (US) | 1999-09-29 | — | — | EP | disclosed |
| US-4935420-A | MICROBIOCIDES, ANTISEPTICS | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| US-4880806-A | BACTERICIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4874764-A | ANTIMICROBIALS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-10-17 | — | — | US | disclosed |
| US-4855292-A | ANTIMICROBIAL AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-08-08 | — | — | US | disclosed |