Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338164 | 0.71 | — | — | |
| SCHEMBL250816 | 0.67 | MEN1 (0.64) | MEN1KMT2AHPGDHSD17B10HCAR3 | |
| SCHEMBL20888860 | 0.62 | KMT2A (0.38) | MEN1KMT2AHPGDHSD17B10HCAR3 | |
| SCHEMBL8875086 | 0.61 | HCAR3 (0.40) | MEN1KMT2AHPGDHSD17B10HCAR3 | |
| SCHEMBL5951859 | 0.60 | FGFR1 (0.52) | HPGDHSD17B10HCAR3TSHR | |
| SCHEMBL21299173 | 0.59 | HCAR3 (0.38) | MEN1KMT2AHPGDHSD17B10HCAR3 | |
| SCHEMBL4342852 | 0.59 | KDM4E (0.43) | HPGDHSD17B10ADORA2AADORA2BADORA1 | |
| SCHEMBL1616707 | 0.58 | MEN1 (0.63) | MEN1KMT2AAXLMKNK1MKNK2 | |
| SCHEMBL7514337 | 0.58 | HSD17B10 (0.58) | MEN1KMT2AHPGDHSD17B10TSHR | |
| SCHEMBL6284930 | 0.57 | MEN1 (0.60) | MEN1KMT2AHPGDHSD17B10HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760370-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5990101-A | Carbapenem derivatives | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0760370-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-03-05 | — | — | EP | disclosed |