Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.49 |
| ▸ | MMP13 | P45452 | 12/20 | 0.49 |
| ▸ | MMP3 | P08254 | 8/20 | 0.49 |
| ▸ | MMP1 | P03956 | 7/20 | 0.49 |
| ▸ | MMP9 | P14780 | 9/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773372 | 1.00 | MMP2 (0.49) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6779301 | 0.92 | MMP2 (0.54) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7489400 | 0.91 | MMP13 (0.53) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6768834 | 0.91 | MMP13 (0.53) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6774034 | 0.90 | MMP2 (0.50) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6775359 | 0.89 | MMP2 (0.48) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6772977 | 0.88 | MMP2 (0.55) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6768238 | 0.88 | MMP2 (0.49) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL6773839 | 0.87 | MMP2 (0.54) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7246126 | 0.86 | MMP2 (0.52) | MMP2MMP13MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165530-A2 | DIHETERO-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051993-A2 | DIHETERO-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |