Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | GAPDH | P04406 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749584 | 1.00 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL13146051 | 1.00 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL3436912 | 0.88 | PRMT5 (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL6426564 | 0.88 | PRMT5 (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL2318607 | 0.88 | PRMT5 (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL29815824 | 0.88 | PRMT5 (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL14946260 | 0.88 | PRMT5 (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL14853754 | 0.88 | PRMT5 (0.65) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL13146052 | 0.87 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL12170639 | 0.87 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (AL) | 2012-06-14 | — | — | US | claimed |
| EP-2430034-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | Southern Research Institute (US) | 2012-03-21 | — | — | EP | claimed |
| WO-2010132513-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | WO | claimed |
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (AL) | 2012-06-14 | — | — | US | disclosed |
| EP-2430034-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | Southern Research Institute (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132513-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SLC29A2, DUT, SLC29A1 | PI4KA 1842/4885PI4K2B 1534/4885PI4K2A 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.