Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 14/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18556821 | 0.92 | VCAM1 (0.75) | VCAM1ALDH1A1KDM4ETHRBHTT | |
| SCHEMBL3705510 | 0.91 | VCAM1 (0.73) | VCAM1ALDH1A1KDM4ETHRBHTT | |
| SCHEMBL10336394 | 0.89 | VCAM1 (0.71) | VCAM1ALDH1A1KDM4ETHRBHTT | |
| SCHEMBL9491262 | 0.89 | VCAM1 (0.71) | VCAM1ALDH1A1KDM4ETHRBHTT | |
| SCHEMBL6261490 | 0.88 | VCAM1 (1.00) | VCAM1ALDH1A1KDM4ETHRB | |
| SCHEMBL20982484 | 0.85 | VCAM1 (0.69) | VCAM1ALDH1A1KDM4E | |
| SCHEMBL30009224 | 0.85 | VCAM1 (0.69) | VCAM1ALDH1A1KDM4E | |
| SCHEMBL30007928 | 0.85 | VCAM1 (0.69) | VCAM1ALDH1A1KDM4ETHRBHTT | |
| SCHEMBL10388965 | 0.85 | VCAM1 (0.69) | VCAM1ALDH1A1KDM4ETHRBHTT | |
| SCHEMBL10389015 | 0.83 | VCAM1 (0.67) | VCAM1ALDH1A1KDM4ETHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242396-A1 | NEW P2X 7 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF INFLAMMATORY, IMMUNE OR CARDIOVASCULAR DISEASES | AstraZeneca AB (SE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044213-A1 | NEW P2X7 RECEPTOR ANTAGONISTS FOR USE IN THE TREATMENT OF INFLAMMATORY, IMMUNE OR CARDIOVASCULAR DISEASES | ASTRAZENECA AB (SE) | 2001-06-21 | — | — | WO | disclosed |