Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 13/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20982484 | 1.00 | VCAM1 (0.69) | VCAM1ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL21253222 | 0.87 | VCAM1 (0.62) | VCAM1ALDH1A1KDM4E | |
| SCHEMBL7496013 | 0.85 | VCAM1 (0.79) | VCAM1ALDH1A1KDM4E | |
| SCHEMBL20982613 | 0.84 | ALDH1A1 (0.68) | VCAM1ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL18556821 | 0.83 | VCAM1 (0.75) | VCAM1ALDH1A1MAPTKDM4E | |
| SCHEMBL6261490 | 0.82 | VCAM1 (1.00) | VCAM1ALDH1A1KDM4E | |
| SCHEMBL22612211 | 0.82 | ALDH1A1 (0.65) | VCAM1ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL30007928 | 0.82 | VCAM1 (0.69) | VCAM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10388965 | 0.82 | VCAM1 (0.69) | VCAM1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3705510 | 0.82 | VCAM1 (0.73) | VCAM1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105601-B | Benzenesulfonamide derivatives and related FERROSTATIN-1 analogs as cell death inhibitors | 维伯VZW公司 | 2022-11-18 | — | — | CN | disclosed |