Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | TTL | Q8NG68 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723221 | 0.69 | JUN (0.42) | JUNLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL7488501 | 0.69 | JUN (0.42) | JUNLMNAPOLBHTTSMN1; SMN2 | |
| SCHEMBL7500228 | 0.67 | — | — | |
| SCHEMBL7922761 | 0.63 | JUN (0.39) | JUNTTLLMNAPOLBHTT | |
| SCHEMBL7497662 | 0.63 | JUN (0.39) | JUNTTLLMNAPOLBHTT | |
| SCHEMBL7974137 | 0.62 | JUN (0.67) | JUN | |
| SCHEMBL7497165 | 0.62 | JUN (0.67) | JUN | |
| Yukonin SCHEMBL7493922 | 0.61 | JUN (0.70) | JUNTTL | |
| SCHEMBL18034519 | 0.60 | JUN (0.40) | JUNTTL | |
| SCHEMBL18034494 | 0.57 | LMNA (0.74) | JUNLMNAPOLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933373-B1 | Terpenoid lactone compounds and their production process | PFIZER (US) | 2002-06-05 | — | — | EP | disclosed |
| US-6391616-B1 | FUNGAL CULTURE FOR USE IN TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DEFECTS | PFIZER INC. | 2002-05-21 | — | — | US | disclosed |
| US-6225339-B1 | FOR THERAPY OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, ENDOTOXEMIA AND/OR TOXIC SHOCK SYNDROME, ACUTE OR CHRONIC INFLAMMATORY DISEASE STATES SUCH AS INFLAMMATORY BOWEL DISEASE; TUBERCULOSIS, ATHEROSCLEROSIS, MUSCLE DEGENERATION, | PFIZER INC. | 2001-05-01 | — | — | US | disclosed |
| US-6221899-B1 | RHEUMATIC DISORDERS; ANTIINFLAMMATORY AGENTS; BONE DISORDERS | PFIZER INC. | 2001-04-24 | — | — | US | disclosed |
| EP-0933373-A1 | Terpenoid lactone compounds and their production process | PFIZER INC. (US) | 1999-08-04 | — | — | EP | disclosed |