Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 11/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497400 | 0.88 | CCR3 (0.64) | CCR3MEN1KMT2APOLB | |
| SCHEMBL7500439 | 0.83 | POLB (0.55) | CCR3MEN1KMT2APOLBACHE | |
| SCHEMBL7498357 | 0.81 | CCR3 (0.60) | CCR3MEN1KMT2APOLBACHE | |
| SCHEMBL6703869 | 0.77 | CCR3 (1.00) | CCR3 | |
| SCHEMBL7499062 | 0.74 | GAA (0.51) | CCR3MEN1KMT2APOLB | |
| SCHEMBL7499525 | 0.73 | CCR3 (0.63) | CCR3 | |
| SCHEMBL7494601 | 0.73 | CCR3 (0.56) | CCR3KMT2AACHE | |
| SCHEMBL7499547 | 0.72 | CCR3 (0.61) | CCR3MEN1KMT2APOLBACHE | |
| SCHEMBL7574762 | 0.72 | CCR3 (0.61) | CCR3 | |
| SCHEMBL7493199 | 0.72 | CCR3 (0.48) | CCR3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140087-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1140087-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035454-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |