Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CCR3 | P51677 | 7/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493199 | 0.89 | CCR3 (0.48) | POLBMEN1KMT2ACCR3 | |
| SCHEMBL7496100 | 0.83 | CCR3 (0.62) | POLBMEN1KMT2ACCR3ACHE | |
| SCHEMBL7497400 | 0.81 | CCR3 (0.64) | POLBMEN1KMT2ACCR3OPRM1 | |
| SCHEMBL7503984 | 0.79 | MEN1 (0.47) | POLBMEN1KMT2ACCR3LMNA | |
| SCHEMBL6705133 | 0.78 | CCR3 (0.77) | POLBMEN1KMT2ACCR3 | |
| SCHEMBL7498357 | 0.78 | CCR3 (0.60) | POLBMEN1KMT2ACCR3ACHE | |
| SCHEMBL7499062 | 0.77 | GAA (0.51) | POLBMEN1KMT2ACCR3 | |
| SCHEMBL7499547 | 0.73 | CCR3 (0.61) | POLBMEN1KMT2ACCR3ACHE | |
| SCHEMBL7494601 | 0.71 | CCR3 (0.56) | KMT2ACCR3ACHE | |
| SCHEMBL7494592 | 0.69 | GAA (0.44) | POLBMEN1KMT2ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140087-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | claimed |
| EP-1140087-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035454-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |