Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7498357 | 0.90 | CCR3 (0.60) | CCR3OPRM1MEN1POLBKMT2A | |
| SCHEMBL7494645 | 0.77 | GAA (0.56) | CCR3OPRM1MEN1POLBKMT2A | |
| SCHEMBL28598370 | 0.77 | OPRM1 (0.81) | OPRM1ACHEGRIN1GRIN2B | |
| SCHEMBL7499853 | 0.76 | CCR3 (0.59) | CCR3OPRM1MEN1KMT2AACHE | |
| SCHEMBL6700268 | 0.76 | CCR3 (1.00) | CCR3MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL28611346 | 0.75 | OPRM1 (1.00) | OPRM1 | |
| SCHEMBL6700148 | 0.74 | CCR3 (1.00) | CCR3MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL7656463 | 0.74 | GAA (0.64) | CCR3OPRM1MEN1KMT2AACHE | |
| SCHEMBL7500439 | 0.73 | POLB (0.55) | CCR3OPRM1MEN1POLBKMT2A | |
| SCHEMBL7496100 | 0.72 | CCR3 (0.62) | CCR3MEN1POLBKMT2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140087-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1140087-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035454-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |