SCHEMBL7496154

SCHEMBL7496154

Nc1ccc2nc(O)nc(O)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.41
ACHE P22303 2/20 0.41
PLAU P00749 2/20 0.39
MAPT P10636 4/20 0.39
KMT2A Q03164 3/20 0.39
ATM Q13315 2/20 0.39
MDM4 O15151 1/20 0.39
TLR9 Q9NR96 1/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
F2 P00734 1/20 0.39
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
MAOA P21397 1/20 0.39
DRD1 P21728 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11209268 0.84 MDM4 (0.52) CTDSP1ACHEPLAUKMT2AMDM4
SCHEMBL11592944 0.81 KDM4E (0.43) CTDSP1ACHEPLAUMAPTKMT2A
SCHEMBL9861710 0.81 LMNA (0.43) CTDSP1ACHEMAPTKMT2AMEN1
SCHEMBL11592377 0.78 KMT2A (0.49) MAPTKMT2AATMTLR9MEN1
SCHEMBL11594604 0.77 KMT2A (0.51) MAPTKMT2AATMTLR9MEN1
SCHEMBL28709841 0.76 KDM4E (0.46) ACHEMAPTKMT2AMEN1HTT
SCHEMBL28821846 0.76
SCHEMBL3498669 0.76 HTT (0.44) ACHEMAPTKMT2AATMMEN1
SCHEMBL29487379 0.76 KDM4E (0.46) ACHEMAPTKMT2AMEN1HTT
SCHEMBL27474146 0.76 LMNA (0.47) MAPTKMT2AMEN1LMNAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997920-A Dyeing polyolefins CIBA-GEIGY CORPORATION (US) 1991-03-05 US claimed
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
EP-0755933-B1 Blue diketopyrrolopyrrole pigments CIBA SC HOLDING AG (CH) 2002-03-27 EP disclosed
US-5817832-A Blue diketopyrrolopyrrole pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-10-06 US disclosed
EP-0755933-A1 Blue diketopyrrolopyrrole pigments Ciba SC Holding AG (CH) 1997-01-29 EP disclosed
EP-0168343-B1 METAL COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING HIGH-MOLECULAR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1991-05-02 EP disclosed
EP-0359708-A2 Monoazo compounds with long-chain alkyl rests CIBA-GEIGY AG (CH) 1990-03-21 EP disclosed
US-4775747-A PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1988-10-04 US disclosed
US-4670486-A Polymer composition pigmented with copper or nickel complexes of ligands containing a semicarbazone moiety CIBA-GEIGY CORPORATION (US) 1987-06-02 US disclosed
US-4639477-A AZO DYES CIBA-GEIGY CORPORATION (US) 1987-01-27 US disclosed
US-4220586-A FASTNESS TO LIGHT, OVER-LACQUERING, MIGRATION, WEATHERING, AND HEAT CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
EP-0010722-A1 Monoazo-compounds, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1980-05-14 EP disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
US-4122117-A Indandione bis-azomethine pigments DAINIPPON INK & CHEMICALS, INC. (JP) 1978-10-24 US disclosed
US-4116959-A ISOINDOLINE PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4052410-A YELLOW, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1977-10-04 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed
US-4012371-A Benzinaldazolyl-, quinolonyl-, or phenmorpholonylazo-3-cyano-4-methyl-1,2-[1',2']-benz-[4',5']-imidazolo-6-hydroxypyridine colorants CIBA-GEIGY CORPORATION (US) 1977-03-15 US disclosed
US-3979386-A YELLOW, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed