Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496154 | 0.84 | CTDSP1 (0.41) | MDM4MEN1LMNAACHEKMT2A | |
| SCHEMBL11690458 | 0.77 | NQO2 (0.53) | MDM4MEN1LMNAACHEKMT2A | |
| SCHEMBL281875 | 0.77 | CHEK1 (0.42) | MDM4MEN1LMNAACHEKMT2A | |
| SCHEMBL2536405 | 0.76 | KDM4E (0.46) | MEN1ACHEKMT2AKCNH2 | |
| SCHEMBL29487338 | 0.76 | MPO (0.41) | ACHEF2HTTPLAUDYRK1A | |
| SCHEMBL3306872 | 0.76 | MPO (0.41) | ACHEF2HTTPLAUDYRK1A | |
| SCHEMBL2082154 | 0.72 | EGFR (0.51) | MDM4MEN1LMNAACHEKMT2A | |
| SCHEMBL17412363 | 0.72 | DHFR (0.51) | MEN1LMNAKMT2AHTTDHFR | |
| SCHEMBL2174621 | 0.72 | MPO (0.47) | MEN1LMNAACHEKMT2ANQO2 | |
| SCHEMBL4092307 | 0.72 | ALDH1A1 (0.42) | MEN1LMNAKMT2AKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101735157-B | Preparation method of erlotinib hydrochloride | SHANGHAI NORTHCAROLINA CHEMLABS CO LTD | 2012-08-22 | — | — | CN | disclosed |
| CN-101735157-A | Preparation method of erlotinib hydrochloride | SHANGHAI NORTHCAROLINA CHEMLAB | 2010-06-16 | — | — | CN | disclosed |
| EP-0010722-B1 | MONOAZO-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-20 | — | — | EP | disclosed |
| US-4312807-A | HEAT RESISTANT PIGMENTS FOR POLYVINYL CHLORIDE AND POLYETHYLENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0010722-A1 | Monoazo-compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-14 | — | — | EP | disclosed |
| US-4012371-A | Benzinaldazolyl-, quinolonyl-, or phenmorpholonylazo-3-cyano-4-methyl-1,2-[1',2']-benz-[4',5']-imidazolo-6-hydroxypyridine colorants | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-3963694-A | AZO PIGMENTS, POLYESTERS, CELLULOSE ETHERS AND ESTERS | CIBA-GEIGY CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
| US-3956266-A | DISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |