SCHEMBL749632

SCHEMBL749632

CCCCC1CCOC(c2ccccc2)(c2ccccc2CO)O1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 3/20 0.39
ADRA1D P25100 3/20 0.39
ADRA1A P35348 3/20 0.39
ADRA1B P35368 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749623 0.97 HTR1A (0.38) HTR1AADRA1DADRA1AADRA1B
SCHEMBL749063 0.96 HTR1A (0.37) HTR1AADRA1DADRA1AADRA1B
SCHEMBL751256 0.93 HTR1A (0.40) HTR1AADRA1DADRA1AADRA1B
SCHEMBL3413055 0.91 HTR1A (0.40) HTR1AADRA1DADRA1AADRA1B
SCHEMBL751251 0.90 HTR1A (0.39) HTR1AADRA1DADRA1AADRA1B
SCHEMBL752340 0.88 ADRA1A (0.42) HTR1AADRA1DADRA1AADRA1B
SCHEMBL750279 0.88 HTR1A (0.41) HTR1AADRA1DADRA1AADRA1B
SCHEMBL3415742 0.88 HTR1A (0.41) HTR1AADRA1DADRA1AADRA1B
SCHEMBL751279 0.87 HTR1A (0.35) HTR1AADRA1DADRA1AADRA1B
SCHEMBL752204 0.87 ADRA1A (0.36) HTR1AADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US claimed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US claimed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed