Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496446 | 1.00 | SSTR4 (0.50) | SSTR4TSHRMEN1KMT2ACD274 | |
| SCHEMBL7496448 | 1.00 | SSTR4 (0.50) | SSTR4TSHRMEN1KMT2ACD274 | |
| SCHEMBL11203028 | 0.75 | NFKB1 (0.51) | SLC6A2LMNA | |
| SCHEMBL1318306 | 0.75 | SSTR4 (0.51) | SSTR4LMNA | |
| SCHEMBL9416715 | 0.75 | SSTR4 (0.42) | SSTR4CD274MAPT | |
| SCHEMBL27294525 | 0.73 | KMT2A (0.72) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL21669843 | 0.72 | SLC6A2 (0.51) | SLC6A2 | |
| SCHEMBL6938281 | 0.71 | GAA (0.45) | SSTR4SLC6A2 | |
| SCHEMBL3253060 | 0.71 | SSTR4 (0.45) | SSTR4CD274 | |
| SCHEMBL31409881 | 0.71 | SSTR4 (0.67) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104411-A4 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-10-24 | — | — | EP | disclosed |
| US-6335338-B1 | Calcilytic compounds | SMITHKLINE BEECHAM CORPORATION | 2002-01-01 | — | — | US | disclosed |
| EP-1104411-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009491-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |