Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 17/20 | 0.45 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297888 | 1.00 | SORD (0.45) | SORDEIF2AK4 | |
| SCHEMBL6299106 | 0.83 | SORD (0.42) | SORD | |
| SCHEMBL6297892 | 0.81 | SORD (0.40) | SORD | |
| SCHEMBL6297889 | 0.79 | SORD (0.41) | SORDEIF2AK4 | |
| SCHEMBL6293329 | 0.79 | SORD (0.41) | SORDEIF2AK4 | |
| SCHEMBL6294405 | 0.78 | SORD (0.56) | SORD | |
| SCHEMBL6294420 | 0.78 | SORD (0.56) | SORD | |
| SCHEMBL7251106 | 0.78 | SORD (0.43) | SORD | |
| SCHEMBL6587251 | 0.77 | HRH4 (0.46) | SORD | |
| SCHEMBL6589084 | 0.77 | HRH4 (0.46) | SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185275-A1 | AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS | Pfizer Products Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000059510-A1 | AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-10-12 | — | — | WO | disclosed |