Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7221815 | 0.90 | KCNH2 (0.38) | LTA4HOPRK1KCNH2DRD2DRD4 | |
| SCHEMBL7221508 | 0.87 | OPRL1 (0.43) | OPRK1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL7685312 | 0.83 | OPRL1 (0.39) | OPRK1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL7222792 | 0.83 | DRD2 (0.41) | DRD2DRD4DRD3OPRL1 | |
| SCHEMBL7228348 | 0.81 | OPRL1 (0.35) | OPRK1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL7221575 | 0.79 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL7890200 | 0.79 | KDM4E (0.37) | OPRK1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL7223226 | 0.78 | HRH3 (0.46) | OPRK1KCNH2DRD2DRD4DRD3 | |
| SCHEMBL8174171 | 0.78 | OPRL1 (0.36) | HCAR2OPRL1 | |
| SCHEMBL8184433 | 0.78 | OPRL1 (0.36) | HCAR2OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | disclosed |